부산대 AI 콜로퀴엄 2025 첫번째 강연을 안내드립니다.

관심 있는 분들의 많은 참석 바랍니다.

장소: 부산대학교 문창회관 105호 및 온라인(Zoom) 

주제: Decoding Cis-Regulatory Elemetns in the Human Genome: Insights into Blood Development, Disorders, and Gene Therapy

연사: Yong Cheng 교수 / St. Jude Children's Research Hospital, USA

강연 요약:

-  Cis-regulatory elements (CREs) are critical for transforming static genomic DNA sequences into dynamic, context-specific gene expression patterns across different cell types, tissues, and developmental stages. Variations in CREs can drive human diseases     and affect health-related traits. Using hematopoiesis as a model system, we leverage computational modeling, multidimensional genomic data integration, and high-throughput genetic perturbation to decode the role of CREs in normal blood    development and related disorders. By combining bioinformatics and engineering-driven approaches with genome editing and gene therapy, we aim to translate these insights into innovative treatments for genetic disorders.

연사 소개:

? Associate Professor, St. Jude Children’s Research Hospital (07/2022 ? Present)

? Assistant Professor, St. Jude Children’s Research Hospital (07/2016 ? 06/2022)

? Post-doctoral scholar, Stanford University (2010 ? 2016)

? Ph.D. in Biochemistry, Microbiology and Molecular Biology, Pennsylvania State University (2009)